![]() ![]() ![]() Other NSAIDs work by blocking some activity of certain prostaglandins: Many NSAIDs work by blocking COX, so fewer prostaglandins are produced: Supporting platelet function (platelets are found in the blood of all mammals and help with blood clotting).Helping maintain blood flow to the kidneys and.Protecting the lining of the stomach and intestines.These substances contribute to pain and inflammation, but they have several positive functions too, including: Like COX, prostaglandins are present throughout the body. Essential to all body functions, enzymes are proteins made by the body and are very specific-each enzyme stimulates a specific reaction that causes a specific result. In the case of the enzyme COX, it stimulates cells to produce several substances, including prostaglandins, after the cells are damaged. COX is present in most body tissues, including the digestive tract (stomach and intestines) and kidneys. When a cell is damaged, an enzyme called cyclooxygenase (COX) is activated. Nonsteroidal anti-inflammatory drugs reduce pain and inflammation by affecting substances that the body releases after cells are damaged. Veterinarians also often use NSAIDs to manage pain after surgery in both dogs and cats. This rubbing can permanently damage the joint and cause pain, inflammation, and lameness. These drugs are widely used in both people and animals for their pain-relieving and anti-inflammatory properties. Veterinarians often prescribe NSAIDS for dogs with osteoarthritis, a condition where cartilage - the protective material that cushions a joint between two bones - breaks down over time, causing the bones to rub against each other. With the notable exception of acetaminophen, all the medications listed in the introduction are nonsteroidal anti-inflammatory drugs, commonly called NSAIDs. A medication meant for you or even for your other dog may not be right for Tinker Bell and may even hurt her. Before reaching for any of the bottles, STOP and call your veterinarian. You also have a few tablets of carprofen left over from when your other dog had knee surgery. You see bottles of aspirin, ibuprofen, naproxen, and acetaminophen-all pain relievers for people. You check the medicine cabinet in your bathroom to see what medications you have that may help her feel better. Your 8-year-old yellow Lab Tinker Bell just came in from the backyard and you notice she’s limping on one of her back legs. Over-the-Counter NSAIDS for People-Are They Safe for Pets? ![]() Benefits of Using FDA-Approved NSAIDs for Dogs and Cats.Side Effects in the Digestive Tract (Stomach and Intestines). ![]()
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